{"product_id":"153795126_product","title":"Retrotransposons And Human Disease: L1 Retrotransposons As A Source Of","description":"New Store Stock\u003cbr\u003e\u003cstrong\u003eAbout this Item\u003c\/strong\u003e\u003cbr\u003e\u003cbr\u003eThe item is a book Hardback\u003cbr\u003eThe Title is Retrotransposons And Human Disease: L1 Retrotransposons As A Source Of Genetic Diversity\u003cbr\u003e\u003cbr\u003eCondition New\u003cbr\u003e\u003cbr\u003eOther Comments\u003cbr\u003eNew Store Stock\u003cbr\u003eContent Language - English                       \r\u003cbr\u003eCategory - SCIENCE \/ Life Sciences \/ Genetics \u0026amp; Genomics\u003cbr\u003eMEDICAL \/ Nursing \/ Oncology \u0026amp; Cancer\u003cbr\u003eSCIENCE \/ Life Sciences \/ Molecular Biology\u003cbr\u003e\u003cbr\u003e\u003cbr\u003eProduct Description -\u003cbr\u003eThirty years ago we knew that retrotransposons made up at least half of our genomes, but  little about their role in biology. The human genome has since been sequenced and the position of all retrotransposons in the reference sequence has been determined. However, as of today, the function of retrotransposons still remains elusive.\r\n\r\n We know much more about the diseases associated with their movement and the host defenses we all have against them.This volume explores an array of diseases in humans associated with L1 retrotransposon movement within the human genome, including some cancers such as colon cancer and neuropsychiatric disorders such as schizophrenia.The chapters explore the diversity of retrotransposons, their different biological mechanisms, the role of L1 in their movement, and their contribution to human diseases. This book posits that somatic events caused by retrotransposons have implications for mosaicism and are often associated with cancers. Germline events are common, occur quite early in development, and are a cause of single gene diseases.\r\n\r\n All in all, the authors implicate L1 retrotransposons as major sources of human diversity and advocate for their continued study.\u003cbr\u003e\u003cp\u003eWhen possible we will add details of the items we are selling to help buyers know what is included in the item for sale. The details are provided automatically from our central master database and can sometimes be wrong.\u003c\/p\u003e\n\n\u003cp\u003eBooks are released in many editions and variations, such as standard edition, re-issue, not for sale, promotional, special edition, limited edition, and many other editions and versions.  The Book you receive could be any of these editions or variations. If you are looking for a specific edition or version please contact us to verify what we are selling.\u003c\/p\u003e\n\n\u003cp\u003e \u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eGift Ideas\u003c\/strong\u003e\u003cbr\u003e\nThis is a great gift idea.\u003c\/p\u003e\n\n\u003cp\u003e \u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eHours of Service\u003c\/strong\u003e\u003cbr\u003e\nWe have many warehouses, some of the warehouses process orders seven days a week, but the Administration Support Staff are located at a head office location, outside of the warehouses, and typically work only Monday to Friday.\u003c\/p\u003e\n\u003cbr\u003eLocation ID 245z\u003cbr\u003e\u003cbr\u003eiHaveit SKU ID 174126901\u003cbr\u003e\u003cbr\u003eUnique Reference Number 2736232897\u003cbr\u003e\u003cbr\u003e","brand":"Abram Gabriel","offers":[{"title":"Default Title \/ unisex","offer_id":45328692052212,"sku":"174126901","price":80.62,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/ihaveitmarketplace.com\/products\/153795126_product","provider":"iHaveit","version":"1.0","type":"link"}